Healthy Beautiful Puppies
Begin w/ Healthy Beautiful Adults!!
What is Genetic Testing? When we have our dogs genetically tested, this testing will tell us if our dogs have any inherited genetic disorders that can be passed on to their litters. Some diseases are recessive and are hidden without any symptoms showing. If two dogs are bred with the same recessive disease, this could be disastrous to the litter. In other cases, some dogs actually have a potentially devastating life threatening disease running through its blood stream. We wouldn't know about any such disease without genetic screening. The great thing about our Genetic Testing is that this is specialized screening. This testing screens for over 160 different diseases and disorders in 16 different areas of the body!! By testing our adult breeding dogs, this will improve the health of our litters because we will know without a doubt if our breeding dogs have any genetic disorders both common to the breed and uncommon. Fyi; you can see for yourself. Below I have posted a few of our dogs Genetic Reports for your review. You may also go to the Embark Website for help & support on understanding how to read the report. Their link is also listed below!
What Disorders/Diseases Do We Test For? While I do test for a variety of information that would seem only important to me as a breeder such as coat type coat color, purity of breed, body features etc; most importantly we screen for all things health. For example: Diseases of the eyes, heart, kidney & bladder. Also any health issues with the skin, skeletal, brain & spinal cord. Also included in the reports are any diseases infecting the blood, immune system, metabolic, neuromuscular & muscular. There are over 160 different diseases that are checked by this testing telling us exactly what is in our dogs Dna. Below please find screening results of our dogs as well as a link to Embark Genetic Labs. For further information feel free to call me at 770-355-3580
Embark Genetic Lab: https://embarkvet.com/our-story/
What Disorders/Diseases Do We Test For? While I do test for a variety of information that would seem only important to me as a breeder such as coat type coat color, purity of breed, body features etc; most importantly we screen for all things health. For example: Diseases of the eyes, heart, kidney & bladder. Also any health issues with the skin, skeletal, brain & spinal cord. Also included in the reports are any diseases infecting the blood, immune system, metabolic, neuromuscular & muscular. There are over 160 different diseases that are checked by this testing telling us exactly what is in our dogs Dna. Below please find screening results of our dogs as well as a link to Embark Genetic Labs. For further information feel free to call me at 770-355-3580
Embark Genetic Lab: https://embarkvet.com/our-story/
CHRISTA'S JUMPY CLOWN MOONBEAM SONATH
"Andy"
Not At Risk!!
Good news! Christa's Jumpy Clown Moonbeam Sonath did not test positive for any of the genetic diseases that Embark screens for.
Not A Carrier!!
Good news! Christa's Jumpy Clown Moonbeam Sonath is not a carrier for any of the genetic diseases that Embark tests for
Genetic Vet Report by Embarkvet.com Test Date: March 24th, 2018
Owner Name: J.M. Pollock Dog Name: Christa's Jumpy Clown Moonbeam Sonath
Sex: Male (intact)
Date of birth: xx/xx/xxxx
Breed type: purebred
Breed: Havanese
Breed registration: American Kennel Club TSxxxxxxx
Genetic summaryGenetic
breed identification: n/a
Predicted adult weight: 13 lbs
Calculated from 17 size genes.
Genetic age: 20 human years
Human equivalent age based on size and other factors.Clinical TraitsThese clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.
Alanine Aminotransferase Activity result: Normal
Christa's Jumpy Clown Moonbeam Sonath has two normal alleles at ALT.
More information on Alanine Aminotransferase Activity:
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity. Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has high ALT levels, please consult your veterinarian.
Health Report
How to interpret these results:AT RISK status: Testing positive (AT RISK) is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.
CARRIER status: This indicates the dog has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if the dog ever has offspring.
Conditions:
Not AT RISK for any conditions tested.
Not a CARRIER for any conditions tested.
All other health conditions testedChrista's Jumpy Clown Moonbeam Sonath tested CLEAR for all these conditions:
"Andy"
Not At Risk!!
Good news! Christa's Jumpy Clown Moonbeam Sonath did not test positive for any of the genetic diseases that Embark screens for.
Not A Carrier!!
Good news! Christa's Jumpy Clown Moonbeam Sonath is not a carrier for any of the genetic diseases that Embark tests for
Genetic Vet Report by Embarkvet.com Test Date: March 24th, 2018
Owner Name: J.M. Pollock Dog Name: Christa's Jumpy Clown Moonbeam Sonath
Sex: Male (intact)
Date of birth: xx/xx/xxxx
Breed type: purebred
Breed: Havanese
Breed registration: American Kennel Club TSxxxxxxx
Genetic summaryGenetic
breed identification: n/a
Predicted adult weight: 13 lbs
Calculated from 17 size genes.
Genetic age: 20 human years
Human equivalent age based on size and other factors.Clinical TraitsThese clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.
Alanine Aminotransferase Activity result: Normal
Christa's Jumpy Clown Moonbeam Sonath has two normal alleles at ALT.
More information on Alanine Aminotransferase Activity:
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity. Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has high ALT levels, please consult your veterinarian.
Health Report
How to interpret these results:AT RISK status: Testing positive (AT RISK) is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.
CARRIER status: This indicates the dog has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if the dog ever has offspring.
Conditions:
Not AT RISK for any conditions tested.
Not a CARRIER for any conditions tested.
All other health conditions testedChrista's Jumpy Clown Moonbeam Sonath tested CLEAR for all these conditions:
- Multidrug Sensitivity (MDR1) (Chromosome 14)
- P2RY12 Defect (P2RY12) (Chromosome 23)
- Factor IX Deficiency, Hemophilia B (F9 Exon 7, Terrier Variant) (Chromosome X)
- Factor IX Deficiency, Hemophilia B (F9 Exon 7, Rhodesian Ridgeback Variant) (Chromosome X)
- Factor VII Deficiency (F7 Exon 5) (Chromosome 22)
- Factor VIII Deficiency, Hemophilia A (F8 Exon 10, Boxer Variant) (Chromosome X)
- Factor VIII Deficiency, Hemophilia A (F8 Exon 11, Shepherd Variant 1) (Chromosome X)
- Factor VIII Deficiency, Hemophilia A (F8 Exon 1, Shepherd Variant 2) (Chromosome X)
- Thrombopathia (RASGRP2 Exon 5, Basset Hound Variant) (Chromosome 18)
- Thrombopathia (RASGRP2 Exon 8) (Chromosome 18)
- Thrombopathia (RASGRP2 Exon 5, American Eskimo Dog Variant) (Chromosome 18)
- Von Willebrand Disease Type II (VWF Exon 28) (Chromosome 27)
- Von Willebrand Disease Type III (VWF Exon 4) (Chromosome 27)
- Von Willebrand Disease Type I (VWF) (Chromosome 27)
- Canine Leukocyte Adhesion Deficiency Type III (FERMT3) (Chromosome 18)
- Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant) (Chromosome 24)
- Canine Elliptocytosis (SPTB Exon 30) (Chromosome 8)
- Cyclic Neutropenia, Gray Collie Syndrome (AP3B1 Exon 20) (Chromosome 31)
- Glanzmann's Thrombasthenia Type I (ITGA2B Exon 13) (Chromosome 9)
- Glanzmann's Thrombasthenia Type I (ITGA2B Exon 12) (Chromosome 9)
- May-Hegglin Anomaly (MYH9) (Chromosome 10)
- Prekallikrein Deficiency (KLKB1 Exon 8) (Chromosome 16)
- Pyruvate Kinase Deficiency (PKLR Exon 5) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 7 Labrador Variant) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 7 Pug Variant) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 7 Beagle Variant) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 10) (Chromosome 7)
- Trapped Neutrophil Syndrome (VPS13B) (Chromosome 13)
- Ligneous Membranitis (PLG) (Chromosome 1)
- Congenital Hypothyroidism (TPO Variant 1) (Chromosome 17)
- Complement 3 (C3) deficiency (C3) (Chromosome 20)
- Severe Combined Immunodeficiency (PRKDC) (Chromosome 29)
- Severe Combined Immunodeficiency (RAG1) (Chromosome 18)
- X-linked Severe Combined Immunodeficiency (IL2RG Variant 1) (Chromosome X)
- X-linked Severe Combined Immunodeficiency (IL2RG Variant 2) (Chromosome X)
- Progressive Retinal Atrophy (PRA) Rod-cone dysplasia, rcd1 (PDE6B Exon 21 Irish Setter Variant) (Chromosome 3)
- Progressive Retinal Atrophy (PRA) Rod-cone dysplasia, rcd1a (PDE6B Exon 21 Sloughi Variant) (Chromosome 3)
- Progressive Retinal Atrophy (PRA) Rod-cone dysplasia, rcd3 (PDE6A) (Chromosome 4)
- Progressive Retinal Atrophy (PRA) (CNGA1 Exon 9) (Chromosome 13)
- Progressive Retinal Atrophy (PRA) Progressive rod-cone degeneration (PRCD Exon 1) (Chromosome 9)
- Progressive Retinal Atrophy (PRA) (CNGB1) (Chromosome 2)
- Progressive Retinal Atrophy (PRA) (SAG) (Chromosome 25)
- Progressive Retinal Atrophy (PRA) Golden Retriever PRA 2 (TTC8) (Chromosome 8)
- Progressive Retinal Atrophy (PRA) Cone-rod dystrophy 1, crd1 (PDE6B) (Chromosome 3)
- Progressive Retinal Atrophy (PRA) Cone-rod dystrophy 2, crd2 (IQCB1) (Chromosome 33)
- Progressive Retinal Atrophy (PRA) Cone-rod dystrophy, crd4/cord1 (RPGRIP1) (Chromosome 15)
- Collie Eye Anomaly, Choroidal Hypoplasia (NHEJ1) (Chromosome 37)
- Day blindness, Achromatopsia, Cone Degeneration (CNGB3 Exon 6) (Chromosome 29)
- Achromatopsia (CNGA3 Exon 7 German Shepherd Variant) (Chromosome 10)
- Achromatopsia (CNGA3 Exon 7 Labrador Retriever Variant) (Chromosome 10)
- Autosomal Dominant Progressive Retinal Atrophy (RHO) (Chromosome 20)
- Canine Multifocal Retinopathy cmr1 (BEST1 Exon 2) (Chromosome 18)
- Canine Multifocal Retinopathy cmr2 (BEST1 Exon 5) (Chromosome 18)
- Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 Deletion) (Chromosome 18)
- Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 SNP) (Chromosome 18)
- Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 9) (Chromosome 20)
- Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 17) (Chromosome 20)
- Glaucoma Primary Open Angle Glaucoma (ADAMTS17 Exon 12) (Chromosome 3)
- Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts (HSF4 Exon 9 Boston Terrier Variant) (Chromosome 5)
- Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts (HSF4 Exon 9 Shepherd Variant) (Chromosome 5)
- Primary Lens Luxation (ADAMTS17) (Chromosome 3)
- Congenital stationary night blindness (RPE65) (Chromosome 6)
- Macular Corneal Dystrophy (MCD) (CHST6) (Chromosome 5)
- 2,8-Dihydroxyadenine (2,8-DHA) Urolithiasis (APRT) (Chromosome 5)
- Cystinuria Type I-A (SLC3A1) (Chromosome 10)
- Cystinuria Type II-A (SLC3A1) (Chromosome 10)
- Cystinuria Type II-B (SLC7A9) (Chromosome 1)
- Hyperuricosuria and Hyperuricemia or Urolithiasis (SLC2A9) (Chromosome 3)
- Polycystic Kidney Disease (PKD1) (Chromosome 6)
- Primary Hyperoxaluria (AGXT) (Chromosome 25)
- Protein Losing Nephropathy (NPHS1) (Chromosome 1)
- X-Linked Hereditary Nephropathy (COL4A5 Exon 35) (Chromosome X)
- Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy (COL4A4 Exon 3) (Chromosome 25)
- Primary Ciliary Dyskinesia (CCDC39 Exon 3) (Chromosome 34)
- Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis (CKCSID), Dry Eye Curly Coat Syndrome (FAM83H Exon 5) (Chromosome 13)
- X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia (EDA Intron 8) (Chromosome X)
- Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND) (FLCN Exon 7) (Chromosome 5)
- Glycogen Storage Disease Type II, Pompe's Disease (GAA) (Chromosome 9)
- Glycogen Storage Disease Type Ia, Von Gierke Disease (G6PC) (Chromosome 9)
- Glycogen Storage Disease Type IIIa (GSD IIIa) (AGL) (Chromosome 6)
- Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 1) (Chromosome 9)
- Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 2) (Chromosome 9)
- Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 5) (Chromosome 6)
- Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 3) (Chromosome 6)
- Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Exon 21) (Chromosome 27)
- Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Exon 8) (Chromosome 27)
- Lagotto Storage Disease (ATG4D) (Chromosome 20)
- Neuronal Ceroid Lipofuscinosis 1 (PPT1 Exon 8) (Chromosome 15)
- Neuronal Ceroid Lipofuscinosis 2 (TPP1 Exon 4) (Chromosome 21)
- Neuronal Ceroid Lipofuscinosis 1 (ARSG Exon 2) (Chromosome 9)
- Neuronal Ceroid Lipofuscinosis 1 (CLN5 Exon 4 Variant 1) (Chromosome 22)
- Neuronal Ceroid Lipofuscinosis 6 (CLN6 Exon 7) (Chromosome 30)
- Neuronal Ceroid Lipofuscinosis 8 (CLN8 Exon 2) (Chromosome 37)
- Neuronal Ceroid Lipofuscinosis (MFSD8) (Chromosome 19)
- Neuronal Ceroid Lipofuscinosis (CLN8) (Chromosome 37)
- Neuronal Ceroid Lipofuscinosis 10 (CTSD Exon 5) (Chromosome 18)
- Neuronal Ceroid Lipofuscinosis (CLN5 Exon 4 Variant 2) (Chromosome 22)
- Adult-Onset Neuronal Ceroid Lipofuscinosis (ATP13A2) (Chromosome 2)
- Gangliosidosis GM1 Gangliosidosis (GLB1 Exon 15 Shiba Inu Variant) (Chromosome 23)
- Gangliosidosis GM1 Gangliosidosis (GLB1 Exon 15 Alaskan Husky Variant) (Chromosome 23)
- Gangliosidosis GM1 Gangliosidosis (GLB1 Exon 2) (Chromosome 23)
- Gangliosidosis GM2 Gangliosidosis (HEXB Exon 3) (Chromosome 2)
- Gangliosidosis GM2 Gangliosidosis (HEXA) (Chromosome 30)
- Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5) (Chromosome 8)
- Autosomal Recessive Amelogenesis Imperfecta (ENAM) (Chromosome 13)
- Persistent Mullerian Duct Syndrome (AMHR2) (Chromosome 27)
- Alaskan Husky Encephalopathy, Subacute Necrotizing Encephalomyelopathy (SLC19A3) (Chromosome 25)
- Alexander Disease (GFAP) (Chromosome 9)
- Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration (SPTBN2) (Chromosome 18)
- Cerebellar Ataxia, Progressive Early-Onset Cerebellar Ataxia (SEL1L) (Chromosome 8)
- Cerebellar Hypoplasia (VLDLR) (Chromosome 1)
- Spinocerebellar Ataxia, Late-Onset Ataxia (CAPN1) (Chromosome 18)
- Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10) (Chromosome 38)
- Benign Familial Juvenile Epilepsy, Remitting Focal Epilepsy (LGI2) (Chromosome 3)
- Degenerative Myelopathy (SOD1A) (Chromosome 31)
- Fetal-Onset Neonatal Neuroaxonal Dystrophy (MFN2) (Chromosome 2)
- Hypomyelination and Tremors (FNIP2) (Chromosome 15)
- Shaking Puppy Syndrome, X-linked Generalized Tremor Syndrome (PLP) (Chromosome X)
- L-2-Hydroxyglutaricaciduria (L2HGDH) (Chromosome 0)
- Neonatal Encephalopathy with Seizures (NEWS) (ATF2) (Chromosome 36)
- Polyneuropathy (NDRG1 Exon 15) (Chromosome 13)
- Polyneuropathy (NDRG1 Exon 4) (Chromosome 13)
- Narcolepsy (HCRTR2 Intron 6) (Chromosome 12)
- Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 15) (Chromosome 1)
- Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 4) (Chromosome 1)
- Juvenile Laryngeal Paralysis and Polyneuropathy (RAB3GAP1) (Chromosome 19)
- Hereditary Sensory Autonomic Neuropathy (HSAN), Acral Mutilation Syndrome (GDNF-AS) (Chromosome 4)
- Juvenile-Onset Polyneuropathy, Leonberger Polyneuropathy 1 (LPN1, ARHGEF10) (Chromosome 16)
- Dilated Cardiomyopathy (PDK4) (Chromosome 14)
- Long QT Syndrome (KCNQ1) (Chromosome 18)
- Muscular Dystrophy Muscular Dystrophy (DMD Cavalier King Charles Spaniel Variant) (Chromosome X)
- Muscular Dystrophy Muscular Dystrophy (DMD Pembroke Welsh Corgi Variant ) (Chromosome X)
- Muscular Dystrophy Muscular Dystrophy (DMD Golden Retriever Variant) (Chromosome X)
- Centronuclear Myopathy (PTPLA) (Chromosome 2)
- Exercise-Induced Collapse (DNM1) (Chromosome 9)
- Inherited Myopathy of Great Danes (BIN1) (Chromosome 19)
- Myotonia Congenita (CLCN1 Exon 7) (Chromosome 16)
- Myotonia Congenita (CLCN1 Exon 23) (Chromosome 16)
- Myotubular Myopathy 1, X-linked Myotubular Myopathy (MTM1) (Chromosome X)
- Hypocatalasia, Acatalasemia (CAT) (Chromosome 18)
- Pyruvate Dehydrogenase Deficiency (PDP1) (Chromosome 29)
- Malignant Hyperthermia (RYR1) (Chromosome 1)
- Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 53) (Chromosome 2)
- Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 8) (Chromosome 2)
- Congenital Myasthenic Syndrome (CHAT) (Chromosome 28)
- Congenital Myasthenic Syndrome (COLQ) (Chromosome 23)
- Episodic Falling Syndrome (BCAN) (Chromosome 7)
- Dystrophic Epidermolysis Bullosa (COL7A1) (Chromosome 20)
- Ectodermal Dysplasia, Skin Fragility Syndrome (PKP1) (Chromosome 7)
- Ichthyosis, Epidermolytic Hyperkeratosis (KRT10) (Chromosome 9)
- Ichthyosis (PNPLA1) (Chromosome 12)
- Ichthyosis (SLC27A4) (Chromosome 9)
- Focal Non-Epidermolytic Palmoplantar Keratoderma, Pachyonychia Congenita (KRT16) (Chromosome 9)
- Hereditary Footpad Hyperkeratosis (FAM83G) (Chromosome 5)
- Hereditary Nasal Parakeratosis (SUV39H2) (Chromosome 2)
- Musladin-Lueke Syndrome (ADAMTSL2) (Chromosome 9)
- Cleft Lip and/or Cleft Palate (ADAMTS20) (Chromosome 27)
- Hereditary Vitamin D-Resistant Rickets (VDR) (Chromosome 27)
- Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia 1 (COL9A3) (Chromosome 24)
- Osteogenesis Imperfecta, Brittle Bone Disease (COL1A2) (Chromosome 14)
- Osteogenesis Imperfecta, Brittle Bone Disease (SERPINH1) (Chromosome 21)
- Osteogenesis Imperfecta, Brittle Bone Disease (COL1A1) (Chromosome 9)
- Osteochondrodysplasia, Skeletal Dwarfism (SLC13A1) (Chromosome 14)
- Skeletal Dysplasia 2 (COL11A2) (Chromosome 12)
- Craniomandibular Osteopathy (CMO) (SLC7A2) (Chromosome 5)
CARRYCOT GEORGINA
"Lizzy"
Not At Risk!!
Good news! Carrycot Georgina did not test positive for any of the genetic diseases that Embark screens for.
Carrier for 1 genetic condition!!
Carrycot Georgina is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?Carrycot Georgina has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Carrycot Georgina ever has children.
Genetic Vet Report by embarkvet.com
Test Date: March 24th
Owner Name: J. M. Pollock
Dog Name: Carrycot Georgina
Sex: Female (intact)
Date of birth: xx/xx/xx
Breed type: purebred
Breed: Havanese
Breed registration: American Kennel Club NPxxxxxx
Genetic summary
Genetic breed identification: n/a
Predicted adult weight: 9 lbs
Calculated from 17 size genes.
Genetic age: 17 human years
Human equivalent age based on size and other factors.Clinical TraitsThese clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.
Alanine Aminotransferase Activity result: Normal
Carrycot Georgina has two normal alleles at ALT.
More information on Alanine Aminotransferase Activity:
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity. Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has high ALT levels, please consult your veterinarian.Health Report
How to interpret these results:AT RISK status: Testing positive (AT RISK) is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.
CARRIER status: This indicates the dog has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if the dog ever has offspring.
Conditions:
Not AT RISK for any conditions tested.
Carrier
System: Ophthalmologic
Condition: Progressive Retinal Atrophy (PRA) Progressive rod-cone degeneration (PRCD Exon 1)
This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are the very beginning of how we see. There are two types of photoreceptors: rods, which gather information about light intensity and are the major contributors to night vision, and cones, which distinguish color and are the major contributors to day vision. In nearly all forms of PRA, the rod cells are affected first, leading to night blindness. They are followed by the cone cells, leading to day blindness. The mechanisms by which the photoreceptors degenerate vary depending on the specific mutation that causes PRA. However, the readout is the same: the dog experiences a slow loss of vision, often leading to complete blindness. PRA is a subtle disease: most owners do not even know that their dog has gone blind--you may notice that your dog is reluctant to go down the stairs, or bumping into door frames or corners, or taking a very long time to fetch a ball or toy. A peek at your dog’s eyes in bright light may also reveal a sluggish pupillary constriction, because the retina is no longer telling your pupils that it is letting in too much light. Diagnosis of PRA can be made by your veterinarian, who can examine the retina’s appearance with ophthalmoscope, or can query its electrical activity with an electroretinogram. Because of the slow progression of PRA, most dogs adapt very well to their condition and remain comfortable in familiar surroundings like their home, backyard, and daily walk route. Over time, many dogs with PRA can develop cataracts. This is thought to be due to buildup of reactive oxygen species and other toxic metabolites released from the dying retinal cells. This can lead to other ophthalmologic conditions and requires close monitoring in consultation with your veterinarian.All other health conditions tested Carrycot Georgina tested CLEAR for all these conditions:
You can learn more on our website embarkvet.com
For enquiries please contact us at [email protected]
"Lizzy"
Not At Risk!!
Good news! Carrycot Georgina did not test positive for any of the genetic diseases that Embark screens for.
Carrier for 1 genetic condition!!
Carrycot Georgina is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?Carrycot Georgina has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Carrycot Georgina ever has children.
Genetic Vet Report by embarkvet.com
Test Date: March 24th
Owner Name: J. M. Pollock
Dog Name: Carrycot Georgina
Sex: Female (intact)
Date of birth: xx/xx/xx
Breed type: purebred
Breed: Havanese
Breed registration: American Kennel Club NPxxxxxx
Genetic summary
Genetic breed identification: n/a
Predicted adult weight: 9 lbs
Calculated from 17 size genes.
Genetic age: 17 human years
Human equivalent age based on size and other factors.Clinical TraitsThese clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.
Alanine Aminotransferase Activity result: Normal
Carrycot Georgina has two normal alleles at ALT.
More information on Alanine Aminotransferase Activity:
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity. Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has high ALT levels, please consult your veterinarian.Health Report
How to interpret these results:AT RISK status: Testing positive (AT RISK) is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.
CARRIER status: This indicates the dog has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if the dog ever has offspring.
Conditions:
Not AT RISK for any conditions tested.
Carrier
System: Ophthalmologic
Condition: Progressive Retinal Atrophy (PRA) Progressive rod-cone degeneration (PRCD Exon 1)
This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are the very beginning of how we see. There are two types of photoreceptors: rods, which gather information about light intensity and are the major contributors to night vision, and cones, which distinguish color and are the major contributors to day vision. In nearly all forms of PRA, the rod cells are affected first, leading to night blindness. They are followed by the cone cells, leading to day blindness. The mechanisms by which the photoreceptors degenerate vary depending on the specific mutation that causes PRA. However, the readout is the same: the dog experiences a slow loss of vision, often leading to complete blindness. PRA is a subtle disease: most owners do not even know that their dog has gone blind--you may notice that your dog is reluctant to go down the stairs, or bumping into door frames or corners, or taking a very long time to fetch a ball or toy. A peek at your dog’s eyes in bright light may also reveal a sluggish pupillary constriction, because the retina is no longer telling your pupils that it is letting in too much light. Diagnosis of PRA can be made by your veterinarian, who can examine the retina’s appearance with ophthalmoscope, or can query its electrical activity with an electroretinogram. Because of the slow progression of PRA, most dogs adapt very well to their condition and remain comfortable in familiar surroundings like their home, backyard, and daily walk route. Over time, many dogs with PRA can develop cataracts. This is thought to be due to buildup of reactive oxygen species and other toxic metabolites released from the dying retinal cells. This can lead to other ophthalmologic conditions and requires close monitoring in consultation with your veterinarian.All other health conditions tested Carrycot Georgina tested CLEAR for all these conditions:
- Multidrug Sensitivity (MDR1) (Chromosome 14)
- P2RY12 Defect (P2RY12) (Chromosome 23)
- Factor IX Deficiency, Hemophilia B (F9 Exon 7, Terrier Variant) (Chromosome X)
- Factor IX Deficiency, Hemophilia B (F9 Exon 7, Rhodesian Ridgeback Variant) (Chromosome X)
- Factor VII Deficiency (F7 Exon 5) (Chromosome 22)
- Factor VIII Deficiency, Hemophilia A (F8 Exon 10, Boxer Variant) (Chromosome X)
- Factor VIII Deficiency, Hemophilia A (F8 Exon 11, Shepherd Variant 1) (Chromosome X)
- Factor VIII Deficiency, Hemophilia A (F8 Exon 1, Shepherd Variant 2) (Chromosome X)
- Thrombopathia (RASGRP2 Exon 5, Basset Hound Variant) (Chromosome 18)
- Thrombopathia (RASGRP2 Exon 8) (Chromosome 18)
- Thrombopathia (RASGRP2 Exon 5, American Eskimo Dog Variant) (Chromosome 18)
- Von Willebrand Disease Type II (VWF Exon 28) (Chromosome 27)
- Von Willebrand Disease Type III (VWF Exon 4) (Chromosome 27)
- Von Willebrand Disease Type I (VWF) (Chromosome 27)
- Canine Leukocyte Adhesion Deficiency Type III (FERMT3) (Chromosome 18)
- Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant) (Chromosome 24)
- Canine Elliptocytosis (SPTB Exon 30) (Chromosome 8)
- Cyclic Neutropenia, Gray Collie Syndrome (AP3B1 Exon 20) (Chromosome 31)
- Glanzmann's Thrombasthenia Type I (ITGA2B Exon 13) (Chromosome 9)
- Glanzmann's Thrombasthenia Type I (ITGA2B Exon 12) (Chromosome 9)
- May-Hegglin Anomaly (MYH9) (Chromosome 10)
- Prekallikrein Deficiency (KLKB1 Exon 8) (Chromosome 16)
- Pyruvate Kinase Deficiency (PKLR Exon 5) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 7 Labrador Variant) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 7 Pug Variant) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 7 Beagle Variant) (Chromosome 7)
- Pyruvate Kinase Deficiency (PKLR Exon 10) (Chromosome 7)
- Trapped Neutrophil Syndrome (VPS13B) (Chromosome 13)
- Ligneous Membranitis (PLG) (Chromosome 1)
- Congenital Hypothyroidism (TPO Variant 1) (Chromosome 17)
- Complement 3 (C3) deficiency (C3) (Chromosome 20)
- Severe Combined Immunodeficiency (PRKDC) (Chromosome 29)
- Severe Combined Immunodeficiency (RAG1) (Chromosome 18)
- X-linked Severe Combined Immunodeficiency (IL2RG Variant 1) (Chromosome X)
- X-linked Severe Combined Immunodeficiency (IL2RG Variant 2) (Chromosome X)
- Progressive Retinal Atrophy (PRA) Rod-cone dysplasia, rcd1 (PDE6B Exon 21 Irish Setter Variant) (Chromosome 3)
- Progressive Retinal Atrophy (PRA) Rod-cone dysplasia, rcd1a (PDE6B Exon 21 Sloughi Variant) (Chromosome 3)
- Progressive Retinal Atrophy (PRA) Rod-cone dysplasia, rcd3 (PDE6A) (Chromosome 4)
- Progressive Retinal Atrophy (PRA) (CNGA1 Exon 9) (Chromosome 13)
- Progressive Retinal Atrophy (PRA) (CNGB1) (Chromosome 2)
- Progressive Retinal Atrophy (PRA) (SAG) (Chromosome 25)
- Progressive Retinal Atrophy (PRA) Golden Retriever PRA 2 (TTC8) (Chromosome 8)
- Progressive Retinal Atrophy (PRA) Cone-rod dystrophy 1, crd1 (PDE6B) (Chromosome 3)
- Progressive Retinal Atrophy (PRA) Cone-rod dystrophy 2, crd2 (IQCB1) (Chromosome 33)
- Progressive Retinal Atrophy (PRA) Cone-rod dystrophy, crd4/cord1 (RPGRIP1) (Chromosome 15)
- Collie Eye Anomaly, Choroidal Hypoplasia (NHEJ1) (Chromosome 37)
- Day blindness, Achromatopsia, Cone Degeneration (CNGB3 Exon 6) (Chromosome 29)
- Achromatopsia (CNGA3 Exon 7 German Shepherd Variant) (Chromosome 10)
- Achromatopsia (CNGA3 Exon 7 Labrador Retriever Variant) (Chromosome 10)
- Autosomal Dominant Progressive Retinal Atrophy (RHO) (Chromosome 20)
- Canine Multifocal Retinopathy cmr1 (BEST1 Exon 2) (Chromosome 18)
- Canine Multifocal Retinopathy cmr2 (BEST1 Exon 5) (Chromosome 18)
- Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 Deletion) (Chromosome 18)
- Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 SNP) (Chromosome 18)
- Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 9) (Chromosome 20)
- Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 17) (Chromosome 20)
- Glaucoma Primary Open Angle Glaucoma (ADAMTS17 Exon 12) (Chromosome 3)
- Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts (HSF4 Exon 9 Boston Terrier Variant) (Chromosome 5)
- Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts (HSF4 Exon 9 Shepherd Variant) (Chromosome 5)
- Primary Lens Luxation (ADAMTS17) (Chromosome 3)
- Congenital stationary night blindness (RPE65) (Chromosome 6)
- Macular Corneal Dystrophy (MCD) (CHST6) (Chromosome 5)
- 2,8-Dihydroxyadenine (2,8-DHA) Urolithiasis (APRT) (Chromosome 5)
- Cystinuria Type I-A (SLC3A1) (Chromosome 10)
- Cystinuria Type II-A (SLC3A1) (Chromosome 10)
- Cystinuria Type II-B (SLC7A9) (Chromosome 1)
- Hyperuricosuria and Hyperuricemia or Urolithiasis (SLC2A9) (Chromosome 3)
- Polycystic Kidney Disease (PKD1) (Chromosome 6)
- Primary Hyperoxaluria (AGXT) (Chromosome 25)
- Protein Losing Nephropathy (NPHS1) (Chromosome 1)
- X-Linked Hereditary Nephropathy (COL4A5 Exon 35) (Chromosome X)
- Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy (COL4A4 Exon 3) (Chromosome 25)
- Primary Ciliary Dyskinesia (CCDC39 Exon 3) (Chromosome 34)
- Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis (CKCSID), Dry Eye Curly Coat Syndrome (FAM83H Exon 5) (Chromosome 13)
- X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia (EDA Intron 8) (Chromosome X)
- Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND) (FLCN Exon 7) (Chromosome 5)
- Glycogen Storage Disease Type II, Pompe's Disease (GAA) (Chromosome 9)
- Glycogen Storage Disease Type Ia, Von Gierke Disease (G6PC) (Chromosome 9)
- Glycogen Storage Disease Type IIIa (GSD IIIa) (AGL) (Chromosome 6)
- Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 1) (Chromosome 9)
- Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 2) (Chromosome 9)
- Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 5) (Chromosome 6)
- Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 3) (Chromosome 6)
- Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Exon 21) (Chromosome 27)
- Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Exon 8) (Chromosome 27)
- Lagotto Storage Disease (ATG4D) (Chromosome 20)
- Neuronal Ceroid Lipofuscinosis 1 (PPT1 Exon 8) (Chromosome 15)
- Neuronal Ceroid Lipofuscinosis 2 (TPP1 Exon 4) (Chromosome 21)
- Neuronal Ceroid Lipofuscinosis 1 (ARSG Exon 2) (Chromosome 9)
- Neuronal Ceroid Lipofuscinosis 1 (CLN5 Exon 4 Variant 1) (Chromosome 22)
- Neuronal Ceroid Lipofuscinosis 6 (CLN6 Exon 7) (Chromosome 30)
- Neuronal Ceroid Lipofuscinosis 8 (CLN8 Exon 2) (Chromosome 37)
- Neuronal Ceroid Lipofuscinosis (MFSD8) (Chromosome 19)
- Neuronal Ceroid Lipofuscinosis (CLN8) (Chromosome 37)
- Neuronal Ceroid Lipofuscinosis 10 (CTSD Exon 5) (Chromosome 18)
- Neuronal Ceroid Lipofuscinosis (CLN5 Exon 4 Variant 2) (Chromosome 22)
- Adult-Onset Neuronal Ceroid Lipofuscinosis (ATP13A2) (Chromosome 2)
- Gangliosidosis GM1 Gangliosidosis (GLB1 Exon 15 Shiba Inu Variant) (Chromosome 23)
- Gangliosidosis GM1 Gangliosidosis (GLB1 Exon 15 Alaskan Husky Variant) (Chromosome 23)
- Gangliosidosis GM1 Gangliosidosis (GLB1 Exon 2) (Chromosome 23)
- Gangliosidosis GM2 Gangliosidosis (HEXB Exon 3) (Chromosome 2)
- Gangliosidosis GM2 Gangliosidosis (HEXA) (Chromosome 30)
- Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5) (Chromosome 8)
- Autosomal Recessive Amelogenesis Imperfecta (ENAM) (Chromosome 13)
- Persistent Mullerian Duct Syndrome (AMHR2) (Chromosome 27)
- Alaskan Husky Encephalopathy, Subacute Necrotizing Encephalomyelopathy (SLC19A3) (Chromosome 25)
- Alexander Disease (GFAP) (Chromosome 9)
- Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration (SPTBN2) (Chromosome 18)
- Cerebellar Ataxia, Progressive Early-Onset Cerebellar Ataxia (SEL1L) (Chromosome 8)
- Cerebellar Hypoplasia (VLDLR) (Chromosome 1)
- Spinocerebellar Ataxia, Late-Onset Ataxia (CAPN1) (Chromosome 18)
- Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10) (Chromosome 38)
- Benign Familial Juvenile Epilepsy, Remitting Focal Epilepsy (LGI2) (Chromosome 3)
- Degenerative Myelopathy (SOD1A) (Chromosome 31)
- Fetal-Onset Neonatal Neuroaxonal Dystrophy (MFN2) (Chromosome 2)
- Hypomyelination and Tremors (FNIP2) (Chromosome 15)
- Shaking Puppy Syndrome, X-linked Generalized Tremor Syndrome (PLP) (Chromosome X)
- L-2-Hydroxyglutaricaciduria (L2HGDH) (Chromosome 0)
- Neonatal Encephalopathy with Seizures (NEWS) (ATF2) (Chromosome 36)
- Polyneuropathy (NDRG1 Exon 15) (Chromosome 13)
- Polyneuropathy (NDRG1 Exon 4) (Chromosome 13)
- Narcolepsy (HCRTR2 Intron 6) (Chromosome 12)
- Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 15) (Chromosome 1)
- Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 4) (Chromosome 1)
- Juvenile Laryngeal Paralysis and Polyneuropathy (RAB3GAP1) (Chromosome 19)
- Hereditary Sensory Autonomic Neuropathy (HSAN), Acral Mutilation Syndrome (GDNF-AS) (Chromosome 4)
- Juvenile-Onset Polyneuropathy, Leonberger Polyneuropathy 1 (LPN1, ARHGEF10) (Chromosome 16)
- Dilated Cardiomyopathy (PDK4) (Chromosome 14)
- Long QT Syndrome (KCNQ1) (Chromosome 18)
- Muscular Dystrophy Muscular Dystrophy (DMD Cavalier King Charles Spaniel Variant) (Chromosome X)
- Muscular Dystrophy Muscular Dystrophy (DMD Pembroke Welsh Corgi Variant ) (Chromosome X)
- Muscular Dystrophy Muscular Dystrophy (DMD Golden Retriever Variant) (Chromosome X)
- Centronuclear Myopathy (PTPLA) (Chromosome 2)
- Exercise-Induced Collapse (DNM1) (Chromosome 9)
- Inherited Myopathy of Great Danes (BIN1) (Chromosome 19)
- Myotonia Congenita (CLCN1 Exon 7) (Chromosome 16)
- Myotonia Congenita (CLCN1 Exon 23) (Chromosome 16)
- Myotubular Myopathy 1, X-linked Myotubular Myopathy (MTM1) (Chromosome X)
- Hypocatalasia, Acatalasemia (CAT) (Chromosome 18)
- Pyruvate Dehydrogenase Deficiency (PDP1) (Chromosome 29)
- Malignant Hyperthermia (RYR1) (Chromosome 1)
- Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 53) (Chromosome 2)
- Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 8) (Chromosome 2)
- Congenital Myasthenic Syndrome (CHAT) (Chromosome 28)
- Congenital Myasthenic Syndrome (COLQ) (Chromosome 23)
- Episodic Falling Syndrome (BCAN) (Chromosome 7)
- Dystrophic Epidermolysis Bullosa (COL7A1) (Chromosome 20)
- Ectodermal Dysplasia, Skin Fragility Syndrome (PKP1) (Chromosome 7)
- Ichthyosis, Epidermolytic Hyperkeratosis (KRT10) (Chromosome 9)
- Ichthyosis (PNPLA1) (Chromosome 12)
- Ichthyosis (SLC27A4) (Chromosome 9)
- Focal Non-Epidermolytic Palmoplantar Keratoderma, Pachyonychia Congenita (KRT16) (Chromosome 9)
- Hereditary Footpad Hyperkeratosis (FAM83G) (Chromosome 5)
- Hereditary Nasal Parakeratosis (SUV39H2) (Chromosome 2)
- Musladin-Lueke Syndrome (ADAMTSL2) (Chromosome 9)
- Cleft Lip and/or Cleft Palate (ADAMTS20) (Chromosome 27)
- Hereditary Vitamin D-Resistant Rickets (VDR) (Chromosome 27)
- Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia 1 (COL9A3) (Chromosome 24)
- Osteogenesis Imperfecta, Brittle Bone Disease (COL1A2) (Chromosome 14)
- Osteogenesis Imperfecta, Brittle Bone Disease (SERPINH1) (Chromosome 21)
- Osteogenesis Imperfecta, Brittle Bone Disease (COL1A1) (Chromosome 9)
- Osteochondrodysplasia, Skeletal Dwarfism (SLC13A1) (Chromosome 14)
- Skeletal Dysplasia 2 (COL11A2) (Chromosome 12)
- Craniomandibular Osteopathy (CMO) (SLC7A2) (Chromosome 5)
You can learn more on our website embarkvet.com
For enquiries please contact us at [email protected]